I honestly don’t know based on what info is available on the product page? Powered via USB, the Micro Metal Gear Motors will likely be fine. They don’t draw that much current so running them with some test code should work OK with the Big Motor Encoder.
If I’m honest I hesitated to reply because I don’t as of yet own any Yukon products. It’s on my wish list, but might be while before I actually pull the trigger.
I do have a Pico Inventor W with two of those motors + Encoders connected with the 6 wire cables. I struggled trying to read them.
How to read encoders on Inventor 2040W - Support - Pimoroni Buccaneers
What is you goal / plan for said motors and the Yukon?