My one criticism of the NVME Base is that it does not offer an easy way to re-flash the SSD. When booting the Pi 4 from an SSD connected via USB, you can just just plug the SSD drive into a PCwith a USB cable to flash the SSD using Pi imager. With this design you need to unscrew the board, remove the NVME drive, insert it in a USB-NVME dock (which is expensive), flash the drive and reassemble. All in all a headache particularly if you need to do it frequently.The alternative is to boot the Pi from the microSD and flash the SSD that way but it involves attaching a display, keboard and mouse which may not be practical for some setups who are only accessing the Pi via SSH.
I would love to see a future design that includes a USB port on the NVME base board to enable easy flashing of the attached NVME drive.