1080p screen?

Hi does anybody know if a 1080p screen (of the right size) would work in the Picade or at least what the problems of using one I might face? I’ve seen plenty of 1080p screens on ebay of roughly the right size.

The reason why is that 5x integer scaling seems to be the holy grail of retro LCD gaming (Obviously retropie would need to support clipping down to 1080p and a custom offset).